4-PYRIDINEBORONIC ACID, PINACOL ESTER

4-PYRIDINEBORONIC ACID, PINACOL ESTER - Names and Identifiers

Name	Pyridine-4-boronic acid pinacol cyclic ester
Synonyms	AKOS BRN-0440 4-PYRIDYLBORONIC ACID PINACOL ESTER 4-Pyridylboronic acid pinacol ester 4-Pyridineboronic acid pinacol ester Pyridine-4-boronic acid pinacol ester 4-PYRIDINEBORONIC ACID, PINACOL ESTER Pyridine-4-Boronic Acid, Pinacol Ester 4-Pyridineboronic acid, pinacol cyclic ester Pyridine-4-boronic acid pinacol cyclic ester 2-(4-PYRIDYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 2-(4-Pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)PYRIDINE 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS	181219-01-2
EINECS	628-005-9
InChI	InChI=1/C11H16BNO2/c1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9/h5-8H,1-4H3
InChIKey	NLTIETZTDSJANS-UHFFFAOYSA-N

4-PYRIDINEBORONIC ACID, PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C11H16BNO2
Molar Mass	205.06
Density	1.03±0.1 g/cm3(Predicted)
Melting Point	149-153 °C (lit.)
Boling Point	300.9±15.0 °C(Predicted)
Flash Point	135.8°C
Water Solubility	Insoluble
Vapor Presure	0.00195mmHg at 25°C
Appearance	White to off-white powder
Color	White to off-white
BRN	7919059
pKa	4.32±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.489
MDL	MFCD01319051

4-PYRIDINEBORONIC ACID, PINACOL ESTER - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns R11 - Highly Flammable
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S16 - Keep away from sources of ignition.
WGK Germany	3
TSCA	No
HS Code	29349990
Hazard Class	IRRITANT

4-PYRIDINEBORONIC ACID, PINACOL ESTER - Reference Information

Uses

4-pyridine boric acid pinacol ester is an organic intermediate, which can be obtained by the reaction of pyridine boric acid and pinacol. Pinacol 4-pyridine borate can be used to prepare a water-soluble fluorescent probe with aggregation-induced luminescence characteristics.

preparation method

0.41g of pyridine boric acid and 0.39g of pinacol are placed in a 50mL round bottom flask, and appropriate
amount of toluene is added as solvent for reflux. During the whole process, the steamed water is continuously released from the system. After 4h, the reaction was stopped and the reaction was completely detected by thin layer chromatography (TLC). The round bottom flask is placed at room temperature
to cool and filter to obtain 0.67g of white solid pyridine borate.

Last Update：2024-04-09 15:16:48